Stefan del Rey Schnitzler | Periodontist

Periodontics and periodontal disease

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Molecular diagnosis in periodontics

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Basic structure of nucleic acids

Nucleic acids are molecules designated to accumulate encode information about cellular functions and structures. DNA or desoxirribonucleic acid is a linear chain composed by units named nucleotides. Each nucleotide consists of a sugar (desoxirribose), a phosphate group and a nitrogen base. There are four distint bases (Adenine, Guanine, Citosine and Timine), so there are four distint nucleotides.

The order of these nucleotides in the chain is very important for genetic code, and is named DNA sequence.

Each DNA chain must be stabilized by other chain that must be complementary. This means that when an A exists in the first chain, a T must appear in the second one, and if G is present in one of them, C must appear in the complementary one. The two chains form a tridimensional structure called DNA duplex.

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